Episode 83: The Truth Behind Mast Cells with Dr. Theoharis Theoharides

In this episode, Haylie Pomroy welcomes Dr. Theoharis Theoharides, a world-renowned expert in pharmacology and internal medicine.

As the Assistant Director of the Integrative Medicine Program at the Institute for Neuro-Immune Medicine, Haylie dives into an intriguing discussion about the complexities of neuroinflammation and chronic illnesses.

Haylie and Dr. Theoharides also explore the difficulties patients face in finding accurate diagnoses, often going through numerous physicians over many years along with the importance of looking beyond superficial symptoms to truly understand and treat patients effectively.

This episode is not only an exploration of mast cells and their role in chronic illness but also an insightful look into the changing landscape of medicine and the need for a more comprehensive, patient-centric approach in healthcare.

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Key points:

00:00 Introduction

04:10 The importance of patient-focused treatment and the complexities of drug interactions in older patients.Β 

09:49 History and functions of mast cells

13:25 Different types of reactions triggered by mast cells

16:21 The importance of accurately identifying mast cell activation symptoms

18:32 Physical indicators of mast cell activation.

24:12 The significant role of the hypothalamus and amygdala in the brain in self-regulation.

27:56 The unique and collaborative approach to neuroinflammation research.

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Theoharis C. Theoharides, MS, MPhil, PhD, MD, is a pioneering figure in the world of pharmacology and internal medicine. At the heart of his career is his role as a Professor at Tufts University School of Medicine in Boston, Massachusetts, where he also leads as the Director of the Molecular Immunopharmacology and Drug Discovery Laboratory. His lab, known as the Theoharis Theoharides Lab at the Sackler School of Graduate Biomedical Sciences, is at the forefront of researching the mechanisms of selective secretion of cytokines and other proinflammatory molecules from mast cells.Β 

Dr. Theoharides's expertise extends into a diverse range of interests including the mechanisms of inflammation, neuroimmunoendocrine disorders, mast cell activation disorders, autism, and Ehlers-Danlos syndrome. His deep understanding and innovative research in these fields have made significant contributions to our understanding of complex medical conditions. Join us as Dr. Theoharides unravels 'The Truth Behind Mast Cells', sharing valuable insights from his extensive research and shedding light on how these tiny cells play a crucial role in various health conditions.

LinkedIn: https://www.linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735